Association between Body Mass Index and Complete Blood Count Parameters

Ghaidaa Rifaat  Hamid; Rayan Zaidan  Khalaf

doi:10.6000/1929-6029.2025.14.33

Authors

Ghaidaa Rifaat Hamid Department of Family and Community Medicine, AL-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq
Rayan Zaidan Khalaf Department of Physiology, AL-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

DOI:

https://doi.org/10.6000/1929-6029.2025.14.33

Keywords:

Body Mass Index, Complete Blood Count

Abstract

Obesity is an abnormal or extraordinary cumulative fat in the body which can lead to health problems. Its prevalence increased worldwide. This study aims to identify the effect of obesity on CBC parameters in obese subjects. Two hundred obese patients of either gender, the mean age was (33.71±2) years, 148 were females (74.4%) and 52 were males (25.6%), each subject submitted to medical history, physical examination, and CBC test. The results of the study revealed that there was a correlation between BMI and CBC parameters, (P value <0.05). This study concluded that there is positive correlation between CBC and BMI (positively correlated, p-value <0.05).

References

Hassan QA, Abdulqader SK, Bakr GM, an, A’wad SN, Abdullah RH, et al. Linking NAFLD and Nephrolithiasis: A CT-Based Investigation. Journal of Contemporary Medical Sciences 2024; 10(4). DOI: https://doi.org/10.22317/jcms.v10i4.1603

Okati-Aliabad H, Ansari-Moghaddam A, Kargar S, Jabbari N. Prevalence of Obesity and Overweight among Adults in the Middle East Countries from 2000 to 2020: A Systematic Review and Meta-Analysis. J Obes 2022; 2022: 8074837. DOI: https://doi.org/10.1155/2022/8074837

Poirier P, Giles TD, Bray GA, Hong Y, Stern JS, Pi-Sunyer FX, et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation 2006; 113(6): 898-918. DOI: https://doi.org/10.1161/CIRCULATIONAHA.106.171016

AL-Jawad FH, Hashim H, Al-Attar Z, Al-Ani AH. Changing the lipid profile and renal functions by Allium sativum, Nigella sativa and Hibiscus sabdariffa in essential hypertensive patients. World J Pharm Phamaceutical Sci 2018; 4: 125-34.

Zeller M, Steg PG, Ravisy J, Lorgis L, Laurent Y, Sicard P, et al. Relation between body mass index, waist circumference, and death after acute myocardial infarction. Circulation 2008; 118(5): 482-90. DOI: https://doi.org/10.1161/CIRCULATIONAHA.107.753483

McGill Jr HC, McMahan CA, Herderick EE, Zieske AW, Malcom GT, Tracy RE, et al. Obesity accelerates the progression of coronary atherosclerosis in young men. Circulation 2002; 105(23): 2712-8. DOI: https://doi.org/10.1161/01.CIR.0000018121.67607.CE

Manson JE, Colditz GA, Stampfer MJ, Willett WC, Rosner B, Monson RR, et al. A prospective study of obesity and risk of coronary heart disease in women. New England Journal of Medicine 1990; 322(13): 882-9. DOI: https://doi.org/10.1056/NEJM199003293221303

Wilson PWF, D'Agostino RB, Sullivan L, Parise H, Kannel WB. Overweight and obesity as determinants of cardiovascular risk: the Framingham experience. Archives of Internal Medicine 2002; 162(16): 1867-72. DOI: https://doi.org/10.1001/archinte.162.16.1867

Tchernof A, Després J-P. Pathophysiology of human visceral obesity: an update. Physiological Reviews 2013. DOI: https://doi.org/10.1152/physrev.00033.2011

Vandanmagsar B, Youm Y-H, Ravussin A, Galgani JE, Stadler K, Mynatt RL, et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nature Medicine 2011; 17(2): 179-88. DOI: https://doi.org/10.1038/nm.2279

Zaid Al-Attar SJ, Imad Hashim. Prevalence of Anemia Types Among Overweight and Obese Patients Attending The Obesity Research and Therapy Unit at AL-Kindy College of Medicine. International Medical Journal 2020; 25(1): 435-48.

Balistreri CR, Caruso C, Candore G. The role of adipose tissue and adipokines in obesity‐related inflammatory diseases. Mediators of Inflammation 2010; 2010(1): 802078. DOI: https://doi.org/10.1155/2010/802078

Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature 2006; 444(7121): 875-80. DOI: https://doi.org/10.1038/nature05487

Levi M, van der Poll T, Schultz M, editors. Infection and inflammation as risk factors for thrombosis and atherosclerosis: Thieme Medical Publishers 2012. DOI: https://doi.org/10.1055/s-0032-1305782

Shimomura I. Enhanced expression of PAI-l in visceral fat: possible contributor to vascular disease in obesity. Nature Medicine 1996; 2: 1-5. DOI: https://doi.org/10.1038/nm0796-800

Tichelaar YIGV, Kluin-Nelemans HJC, Meijer K. Infections and inflammatory diseases as risk factors for venous thrombosis. Thromb Haemost 2012; 107(05): 827-37. DOI: https://doi.org/10.1160/TH11-09-0611

Rydberg E, Arlbrandt M, Gudmundsson P, Erhardt L, Willenheimer R. Left atrioventricular plane displacement pre-dicts cardiac mortality in patients with chronic atrial fibri-llation. International Journal of Cardiology 2003; 91(1): 1-7. DOI: https://doi.org/10.1016/S0167-5273(02)00578-8

Hung S-P, Chen C-Y, Guo F-R, Chang C-I, Jan C-F. Combine body mass index and body fat percentage measures to improve the accuracy of obesity screening in young adults. Obesity Research & Clinical Practice 2017; 11(1): 11-8. DOI: https://doi.org/10.1016/j.orcp.2016.02.005

Spyrou N, Avgerinos KI, Mantzoros CS, Dalamaga M. Classic and novel adipocytokines at the intersection of obesity and cancer: diagnostic and therapeutic strategies. Current Obesity Reports 2018; 7: 260-75. DOI: https://doi.org/10.1007/s13679-018-0318-7

Al-Sattam Z, Hassan S, Majeed B, Al-Attar Z. Knowledge about anemia in pregnancy among females attending primary health care centers in Baghdad. Open Access Macedonian Journal of Medical Sciences 2022; 10(B): 785-92. DOI: https://doi.org/10.3889/oamjms.2022.8506

Argyrakopoulou G, Dalamaga M, Spyrou N, Kokkinos A. Gender differences in obesity-related cancers. Current Obesity Reports 2021; 10: 100-15. DOI: https://doi.org/10.1007/s13679-021-00426-0

Lee YJ, Shin YH, Kim JK, Shim JY, Kang DR, Lee HR. Metabolic syndrome and its association with white blood cell count in children and adolescents in Korea: the 2005 Korean National Health and Nutrition Examination Survey. Nutrition, Metabolism and Cardiovascular Diseases 2010; 20(3): 165-72. DOI: https://doi.org/10.1016/j.numecd.2009.03.017

Hadaegh F, Azizi F. Effect of Weight Change on Incident of metabolic syndrome and its components according to Iranian Waist circumference and NHLBI: TLGS. Iranian Journal of Endocrinology and Metabolism 2010; 12(2): 116-30.

Karastergiou K, Mohamed-Ali V. The autocrine and paracrine roles of adipokines. Molecular and Cellular Endocrinology 2010; 318(1-2): 69-78. DOI: https://doi.org/10.1016/j.mce.2009.11.011

Lafontan M. Fat cells: afferent and efferent messages define new approaches to treat obesity. Annu Rev Pharmacol Toxicol 2005; 45(1): 119-46. DOI: https://doi.org/10.1146/annurev.pharmtox.45.120403.095843

Cinti S, Mitchell G, Barbatelli G, Murano I, Ceresi E, Faloia E, et al. Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. Journal of Lipid Research 2005; 46(11): 2347-55. DOI: https://doi.org/10.1194/jlr.M500294-JLR200

Zhang S, Liu Q, Wang J, Harnish DC. Suppression of interleukin-6-induced C-reactive protein expression by FXR agonists. Biochemical and Biophysical Research Communications 2009; 379(2): 476-9. DOI: https://doi.org/10.1016/j.bbrc.2008.12.117

Al-Jawad FH, Al-Attar Z, Abbood MS. The Protective Effect of Nitroglycerin, N-Acetyl Cysteine and Metoprolol in CCL4 Induced Animal Model of Acute Liver Injury. Open Access Maced J Med Sci 2019; 7(11): 1739-43. DOI: https://doi.org/10.3889/oamjms.2019.469