Synthesis and Characterization of N-Substituted Tetrahydroiso-quinoline Derivatives via a Pictet-Spengler Condensation
DOI:
https://doi.org/10.6000/1929-5030.2014.03.03.5Keywords:
Tetrahydroisoquinoline, Pictet-Spengler reaction, Imine, Trifluoroacetic acid.Abstract
Synthesis of N-substituted 1,2,3,4 –tetrahydroisoquinoline derivatives and bis-isoquinoline has been carried out via a Pictet-Spengler condensation. Tetrahydroisoquinolines were obtained from 2-(3',4'-dimethoxyphenyl) ethylamine in four steps. The entire synthesized compounds were characterized by IR, 1H NMR and mass spectral data.
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Published
2014-09-18
How to Cite
Patel, H. A., & Patel, A. L. (2014). Synthesis and Characterization of N-Substituted Tetrahydroiso-quinoline Derivatives via a Pictet-Spengler Condensation. Journal of Applied Solution Chemistry and Modeling, 3(3), 169–174. https://doi.org/10.6000/1929-5030.2014.03.03.5
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