The Relationship Between Urinary Stone Disease and Nutrition Type in Infants
DOI:
https://doi.org/10.6000/1929-4247.2022.11.01.1Keywords:
Breastfeeding, formula, infant, urinary system stone, supplementary food, Vitamin D, family historyAbstract
The relationship between urinary stone disease and nutrition in infants is not well known. This study investigates the relationship between breast milk, formula and supplementary foods, vitamin D usage, and family stone history with urinary system stones in children aged 3-24 months. The study included 100 infants aged 3-24 months of age with urinary tract stones and 40 healthy infants with similar age and gender as the control group. Sixty of the patients were boys, and 40 were girls; the control group consisted of 26 boys and 16 girls. There was no significant difference in only breastfeeding, breastfeeding plus formula, and formula feeding in the patients and controls. Positive family history of urolithiasis was significantly higher in the patients compared to the controls (p=0.04). While breastfeeding duration time was negatively correlated with spot urine calcium to creatinine ratio in children exclusively breastfed infants. No direct effect of nutrition type and vitamin D usage on stone formation was found in infants. It has been shown that stone formation in this age group is associated with a family history of stones. In this study, the duration of breastfeeding is negatively correlated with the spot urinary calcium to creatinine ratio.
References
Sas DJ. An update on the changing epidemiology and metabolic risk factors in pediatric kidney stone disease. Clin J Am Soc Nephrol 2011; 6: 2062-2068. https://doi.org/10.2215/CJN.11191210
Dwyer ME, Krambeck AE, Bergstralh EJ, Milliner DS, Lieske JC, Rule AD. Temporal trends in incidence of kidney Stones among children: a 25-year population-based study. J Urol 2012; 188: 247-252. https://doi.org/10.1016/j.juro.2012.03.021
Matlaga BR, Schaeffer AJ, Novak TE, Trock BJ. Epidemiologic insights into pediatric kidney stone disease. Urol Res 2010; 38: 453-457. https://doi.org/10.1007/s00240-010-0327-9
Rizvi SA, Naqvi SA, Hussain Z, Hashmi A, Hussain M, Zafar MN, Sultan S, Mehdi H. Pediatric urolithiasis: developing nation perspectives. J Urol 2002; 168: 1522-1525. https://doi.org/10.1016/S0022-5347(05)64509-0
Ertan P, Tekin G, Oger N, Alkan S, Horasan GD. Metabolic and demographic characteristics of children with urolithiasis in Western Turkey. Urol Res 2010; 39: 105-110. https://doi.org/10.1007/s00240-010-0306-1
Oner A, Demircin G, Ipekçioğlu H, Bülbül M, Ecin N. Etiological and clinical patterns of urolithiasis in Turkish children. Eur Urol 1997; 31: 453-458. https://doi.org/10.1159/000474506
Baştuğ F, Gündüz Z, Tülpar S, Poyrazoğlu H, Düşünsel R. Urolithiasis in infants: evaluation of risk factors. World J Urol 2013; 31: 1117-1122. https://doi.org/10.1007/s00345-012-0828-y
Alpay H, Gokce I, Ozen A, Bıyıklı N. Urinary stone disease in the first year of life: is it dangerous? Pediatr Surg Int 2013; 29: 311-316. https://doi.org/10.1007/s00383-012-3235-y
Jobs K, Rakowska M, Paturej A. Urolithiasis in the pediatric population-current opinion on epidemiology, patophysiology, diagnostic evaluation and treatment. Dev Period Med 2018; 22: 201-208.
Önal B, Kırlı EA, Canpolat N, Taşdemir M, Gürbüz A, Özman O, Sever L, Bilge I, Çalışkan S. Different approaches among physicians to treat pediatric stone disease: a survey-based study. Arch Argent Pediatr 2021; 119: 83-90. https://doi.org/10.5546/aap.2021.eng.83
Sas DJ. Dietary risk factors for urinary stones in children. Curr Opin Pediatr 2020; 32: 284-287. https://doi.org/10.1097/MOP.0000000000000886
Mohamed J, Riadh M, Abdellatif N. Urolithiasis in infants. Pediatr Surg Int 2007; 23: 295-299. https://doi.org/10.1007/s00383-007-1889-7
Nicoletta JA, Lande MB. Medical evaluation and treatment of urolithiasis. Pediatr Clin North Am 2006; 53: 479-91. https://doi.org/10.1016/j.pcl.2006.03.001
Alzaheb RA. A Review of the factors associated with the timely initiation of breastfeeding and exclusive breastfeeding in the Middle East. Clin Med Insights Pediatr 2017; 11: 1179556517748912. https://doi.org/10.1177/1179556517748912
Gertosio C, Meazza C, Pagani S, Bozzola M. Breastfeeding and its gamut of benefits. Minerva Pediatr 2016; 68: 201-212.
Greer F. Do breast fed infants need supplemental vitamins. Pediatr Clin N Am 2000; 48: 415-423. https://doi.org/10.1016/S0031-3955(08)70034-8
Bozkurt HB, Çetin T, Sarıca K. The Possible Beneficial Effect of Breastfeeding on the Clinical Course of Urolithiasis Detected During Infancy. Breastfeed Med 2020; 15: 84-89. https://doi.org/10.1089/bfm.2019.0236
Drach GW. Metabolic evaluation of pediatric patients with stones. Urol Clin North Am 1995; 22: 95-100. https://doi.org/10.1016/S0094-0143(21)01019-3
Edvardsson V, Elidottir H, Indridason OS, Palsson R. High incidence of kidney stones in Icelandic children. Pediatr Nephrol 2005; 20: 940-944. https://doi.org/10.1007/s00467-005-1861-5
Ozokutan BH, Kucukaydin M, Gunduz Z, Kabaklioglu M, Okur H, Turan C. Urolithiasis in childhood. Pediatr Surg Int 2000; 16: 60-63. https://doi.org/10.1007/s003830050016
Basaklar AC, Kale N. Experience with childhood urolithiasis, report of 196 cases. Br J Urol 1991; 67: 203-205. https://doi.org/10.1111/j.1464-410X.1991.tb15110.x
Dursun I, Poyrazoglu HM, Dusunsel R, Gunduz Z, Gurgoze MK, Demirci D, Kucukaydin M. Pediatric urolithiasis: an 8-year experience of single centre. Int Urol Nephrol 2008; 40: 3-9. https://doi.org/10.1007/s11255-007-9234-6
Novak TE, Lakshmanan Y, Trock BJ, Gearhart JP, Matlaga BR. Sex prevalence of pediatric kidney stone disease in the United States: an epidemiologic investigation. Urology 2009; 74: 104-107. https://doi.org/10.1016/j.urology.2008.12.079
Daudon M, Doré JC, Jungers P, Lacour B. Changes in stone composition according to age and gender of patients: a multivariate epidemiological approach. Urol Res 2004; 32: 241-247. https://doi.org/10.1007/s00240-004-0421-y
Taylor EN, Curhan GC. Diet and fluid prescription in stone disease. Kidney Int 2006; 70: 835-839. https://doi.org/10.1038/sj.ki.5001656
Taylor EN, Fung TT, Curhan GC. DASH-Style diet associates with reduced risk for kidney stones. J Am Soc Nephrol 2009; 20: 2253-2259. https://doi.org/10.1681/ASN.2009030276
Nouvenne A, Meschi T, Prati B, Guerra A, Allegri F, Vezzoli G, Soldati L, Gambaro G, Maggiore U, Borghi L. Effects of a low-salt diet on idiopathic hypercalciuria in calcium-oxalate stone formers: a 3-mo randomized controlled trial. Am J Clin Nutr 2010; 91: 565-570. https://doi.org/10.3945/ajcn.2009.28614
Curhan GC, Willett WC, Speizer FE, Spiegelman D, Stampfer MJ. Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk for kidney stones in women. Ann Intern Med 1997; 126: 497-504. https://doi.org/10.7326/0003-4819-126-7-199704010-00001
Hoppe B, Roth B, Bauerfed C, Langman BC. Oxalate, citrate, and sulfate concentration in human milk compared with Formula preparations: Influence on urinary anion excretion. J Pediatr Gastroenterol Nutr 1998; 27: 383-386. https://doi.org/10.1097/00005176-199810000-00002
Campfield T, Braden G, Flynn-Valone P, Clark N. Urinary oxalate excretion in premature infants: Effect of human milk versus formula feeding. Pediatrics 1994; 94: 674-678. https://doi.org/10.1542/peds.94.5.674
Erbagci A, Erbagci AB, Yilmaz M, Yagci F, Tarakcioglu M, Yurtseven C, Koyluoglu O, Sarica K. Pediatric urolithiasis evaluation of risk factors in 95 children. Scand J Urol Nephrol 2003; 37: 129-133. https://doi.org/10.1080/00365590310008866
Tabel Y, Akin IM, Tekin S. Clinical and demographic characteristics of children with urolithiasis: single-center experience from eastern Turkey. Urol Int 2009; 83: 217-221. https://doi.org/10.1159/000230027
Hoppe B, Kemper MJ. Diagnostic examination of the child with urolithiasis or nephrocalcinosis. Pediatr Nephrol 2010; 25: 403-413. https://doi.org/10.1007/s00467-008-1073-x
Ece A, Ozdemir E, Gurkan F, Dokucu AI, Akdeniz O. Characteristics of pediatric urolithiasis in south-east Anatolia. Int J Urol 2000; 7: 330-334. https://doi.org/10.1046/j.1442-2042.2000.00207.x
Amancio L, Fedrizzi M, Bresolin NL, Penido MG. Pediatric urolithiasis: experience at a tertiary care pediatric hospital. J Bras Nefrol 2016; 38: 90-98. https://doi.org/10.5935/0101-2800.20160014
Fallahzadeh MH, Zare J, Al-Hashemi GH, Derakhshan A, Basiratnia M, Arasteh MM Fallahzadeh MA, Fallahzadeh MK. Elevated serum levels of Vitamin D in infants with urolithiasis. Iran J Kidney Dis 2012; 6: 186-191.
Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M. Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics 2008; 122: 398-417. https://doi.org/10.1542/peds.2007-1894
Bastug F, Dusunsel R. Pediatric urolithiasis: causative factors, diagnosis, and medical management. Nat Rev Urol 2012; 9: 138-146. https://doi.org/10.1038/nrurol.2012.4
Üntan İ, Üntan S, Tosun H, Demirci D. Metabolic risk factors and the role of prophylaxis in pediatric urolithiasis. J Pediatr Urol 2021; 17: 215.e1-215.e6. https://doi.org/10.1016/j.jpurol.2020.12.003
Tekin A, Tekgul S, Atsu N, Bakkaloglu M, Kendi S. Oral potassium citrate treatment for idiopathic hypocitruria in children with calcium urolithiasis. J Urol 2002; 168: 2572-2574. https://doi.org/10.1016/S0022-5347(05)64218-8
Tekin A, Tekgul S, Atsu N, Sahin A, Ozen H, Bakkaloglu M. A study of the etiology of idiopathic calcium urolithiasis in children: hypocitruria is the most important risk factor. J Urol 2000; 164: 162-165. https://doi.org/10.1016/S0022-5347(05)67487-3
Pietrow PK, Pope JC 4th, Adams MC, Shyr Y, Brock JW 3rd. Clinical outcome of pediatric stone disease. J Urol 2002; 167: 670-673. https://doi.org/10.1016/S0022-5347(01)69121-3
Wen JG, Liu XJ, Wang ZM, Li TF, Wahlqvist ML. Melamine-contaminated milk formula and its impact on children. Asia Pac J Clin Nutr 2016; 25: 697-705.
Butani L, Kalia A. Idiopathic hypercalciuria in children--how valid are the existing diagnostic criteria? Pediatr Nephrol 2004; 19: 577-582. https://doi.org/10.1007/s00467-004-1470-8
Hulton SA. Evaluation of urinary tract calculi in children. Arch Dis Child 1982; 84: 320-323. https://doi.org/10.1136/adc.84.4.320
Rao PN, Prendiville V, Buxton A, Moss DG, Blacklock NJ. Dietary management of urinary risk factors in renal stone formers. Br J Urol 1982; 54: 578-583. https://doi.org/10.1111/j.1464-410X.1982.tb13600.x
Polito C, La Manna A, Maiello R, Nappi B, Siciliano MC, Di Domenico MR, Di Toro R. Urinary sodium and potassium excretion in idiopathic hypercalciuria of children. Nephron 2002; 91: 7-12. https://doi.org/10.1159/000057598
Matos V, Van Melle G, Werner D. Urinary oxalate and urate to creatinine ratios in a healthy pediatric population. Am J Kidney Dis 1999; 34: 1-7. https://doi.org/10.1016/S0272-6386(99)70380-X
Kirejczyk JK, Porowski T, Konstantynowicz J, Kozerska A, Nazarkiewicz A, Hoppe B, Wasilewska A. Urinary citrate excretion in healthy children depends on age and gender. Pediatr Nephrol 2014; 29: 157515-82. https://doi.org/10.1007/s00467-014-2806-7
Del Valle EE, Spivacow FR, Negri AL. Citrate and renal stones. Medicina (B Aires) 2013; 73: 363-368.
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