Fructans and Mineral Nutrition
DOI:
https://doi.org/10.6000/1929-5634.2016.05.03.2Keywords:
Fructans, minerals, absorption, deficiency, nutrition.Abstract
Fructan molecules have a history of more than 150 years and ancient peoples used fructans containing plants as food, feed or medicine. The modern history of fructans began with their discovery by Rose (1804) and known at the turn of the 20th century considerable development with Edelman's proposal concerning their metabolism in higher plant. At present time, fructans are considered food not food ingredients, and are found in more than 500 food products resulting in significant daily consumption. Because the science of nutrition itself has changed, fructans are now considered as functional foods and the passionate history of their health benefits continues to arise interest of scientists. Contrary to the fact that non-digestible carbohydrates have been accused of causing an impairment in the small intestine absorption of minerals, research conducted during the last three decades demonstrated that fructans enhanced mineral absorption, and the scientific evidence claiming that fructans enhance mineral absorption is based on both animal and human experiments which are very conclusive. Although different hypotheses have been proposed to explain the roles of fructans in enhancing minerals absorption, the mechanisms behind this enhancement are still unclear, even though investigation have demonstrated that different fructans-related mechanisms may be involved in the increased absorption of minerals due to fructans intake. This review paper aims to report on the recent development and the roles of fructans in enhancing mineral absorption and their deficiencies prevention.
References
[1] Meier H, Reid JS. Reserve polysaccharides other than starch in higher plants. In: Loewus FA, Tanner W, editors. Encyclopaedia of plant physiology. New Series. Berlin: Springer Verlag 1982; p. 418-71.
http://dx.doi.org/10.1007/978-3-642-68275-9_11
[2] Pontis HG, Del Campillo E. Fructan. In: Dey PM, Dixon RA, editors. Biochemistry of storage carbohydrates in green plants. London: Academic Press 1985; p. 205-27.
[3] Pollock CJ, Cairns AJ. Fructan metabolism in grasses and cereals. Annu Rev Plant Physiol Plant Mol Biol 1991; 42: 77-101.
http://dx.doi.org/10.1146/annurev.pp.42.060191.000453
[4] Duggan C, Gannon J, Walker WA. Protective nutrients and functional foods for the gastrointestinal tracts. Am J Clin Nutr 2002; 75: 789-808.
[5] Roberfroid MB. Functional foods: concepts and application to inulin and oligofructose. Br J Nutr 2002; 87 (Suppl. 2): S139-43.
http://dx.doi.org/10.1079/BJN/2002529
[6] Yun JW. Fructooligosaccharides – occurrence, preparation, and application. Enz Microbial Technol 1996; 19: 107-17.
http://dx.doi.org/10.1016/0141-0229(95)00188-3
[7] IUB-IUPAC Joint Commission on Biochemical Nomenclature (JCBN). Abbreviated terminology of oligosaccharide chains. Recommendations 1980. J Biol Chem 1982; 257: 3347-51.
[8] Lewis DH. Nomenclature and diagrammatic representation of oligomeric fructans- a paper for discussion. New Phytol 1993; 124: 583-94.
http://dx.doi.org/10.1111/j.1469-8137.1993.tb03848.x
[9] Waterhouse AL, Chatterton NJ. Glossary of fructan terms. In: Suzuki M, Chatterton NJ, editors. Science and technology of fructans. Boca Raton (FL): CRC Press 1993; p. 1-7.
[10] Shiomi N. Structure of fructo-polysaccharide (asparagosin) from roots of asparagus (Asparagus officinalis L.). New Phytol 1993; 123: 263-70.
http://dx.doi.org/10.1111/j.1469-8137.1993.tb03734.x
[11] Shiomi N, Onodera S, Chatterton NJ, Harrison PA. Separation of fructooligosaccharide isomers by anion-exchange chromatography. Agric Biol Chem 1991; 55: 1427-8.
[12] Shiomi N, Onodera S, Sakai H. Fructo–oligosaccharide content and fructosyltransferase activity during growth of onion bulbs. New Phytol 1997; 136: 105-13.
http://dx.doi.org/10.1111/j.1469-8137.1997.tb04736.x
[13] Stahl B, Linos A, Karas M, Hillenkamp F, Steup M. Analysis of fructans from higher plants by matrix-assisted laser desorption/ionization mass spectrometry. Anal Biochem 1997; 246: 195-204.
http://dx.doi.org/10.1006/abio.1997.2011
[14] WCRF-AICR (World Cancer Research Fund-American Institute of Cancer Research). Food, nutrition and the prevention of cancer: a global perspective. 2007. [Cited 2016 August 5]. Available from: http://www.aicr.org/research/ research_science_expert_report.html
[15] Ness AR, Powles JW. Fruits and vegetables, and cardiovascular disease: A review. Int J Epidemiol 1997; 26: 1-13.
http://dx.doi.org/10.1093/ije/26.1.1
[16] Joshipura KJ, Ascherio A, Mansun J, et al. Fruit and vegetable intake in relation to risk of ischaemic stroke. J Am Med Assoc 1999; 282: 1233-9.
http://dx.doi.org/10.1001/jama.282.13.1233
[17] Johnsen SP, Overvad K, Stripp C, Tjonneland A, Husted SE, Sorensen HT. Intake of fruit and vegetable and the risk of ischaemic stroke in a cohort of Danish men and woman. Am J Clin Nutr 2003; 78: 57-64.
[18] Appel LJ, Moore TJ, Obarzanek E, et al. A clinical trial of the effects of dietary patterns on blood pressure. New Engl J Med 1997; 336: 1117-24.
http://dx.doi.org/10.1056/NEJM199704173361601
[19] Block J, Patterson B, Subar A. fruits, vegetables and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 1992; 18: 1-29.
http://dx.doi.org/10.1080/01635589209514201
[20] Hertog MG, Bueno de Mesquita GB, Fehily A, Sweetnam PM, Elwood PC, Kroumhout D. Fruit and vegetable consumption and cancer mortality in the C aerphilly study. Epidemiol Biomarkers Prev 1996; 5: 673-7.
[21] Olsen M, Gudmand-heyer E. Efficacy, safety, and tolerability of fructooligosaccharides in the treatment of irritable bowel syndrome. Am J Clin Nutr 2000; 72: 1570-5.
[22] Flamm G, Glinsman W, Kritchevsky D, Prosky L, Roberfroid M. Inulin and oligofructose as dietary fiber: A review of the evidence. Crit Rev Food Sci Nutr 2001; 45: 353-62.
http://dx.doi.org/10.1080/20014091091841
[23] Cherbut C. Inulin and oligofructose in the dietary fiber concept. Br J Nutr 2002; 87 (Suppl. 2): S159-62.
http://dx.doi.org/10.1079/BJN2002532
[24] Mitsuoka T, Hidaka H, Eida T. Effects of fructo-oligosaccharides on intestinal microflora. Nahrung 1987; 31: 427-36.
http://dx.doi.org/10.1002/food.19870310528
[25] Spiegel JE, Rose R, Karabell P, Franks VH, Schmitt DF. Safety and benefits of fructooligosaccharides as food ingredients. Food Technol 1994; 1: 85-9.
[26] Tashiro Y, Eida T, Hidaka H. Distribution and quantification of fructooligosaccharides in food materials. Sci Rep Meiji Seiki Kaisha 1992; 31: 35-40.
[27] Tomomatsu H. Health effects of oligosaccharides. Food Technol 1994; 10: 61-5.
[28] Buddington RK, Williams CH, Chen SC, Witherly SA. Dietary supplement of neosugar alters fecal flora and decreases activities of some reductive enzymes in human subjects. Am J Clin Nutr 1996; 63: 709-16.
[29] Farnworth ER. Fructans in human and animal diet. In: Suzuki M, Chatterton NJ, editors. Science and technology of fructans. Boca Raton (FL): CRC Press, 1993; p. 257- 72.
[30] Scheppach W, Luehrs H, Menzel T. Beneficial health effects of low-digestible carbohydrate consumption. Br J Nutr 2001; 85 (Suppl. 1): S23-30.
http://dx.doi.org/10.1079/BJN2000259
[31] Ellegård L, Andersson H, Bosaeus I. Inulin and oligofructose do not influence the absorption of cholesterol, or the excretion of cholesterol, Ca, Mg, Zn, Fe, or bile acids but increases energy excretion in ilestomy subjected. Eur J Clin Nutr 1997; 41: 1-5.
http://dx.doi.org/10.1038/sj.ejcn.1600320
[32] van den Heuvel EGMH, Schaafsma G, Muys T, van Dokkun W. Nondigestible oligosaccharides do not interfere with calcium and nonheme-iron absorption in young, healthy men. Am J Clin Nutr 1998; 67: 445-51.
[33] van den Heuvel EGMH, Muys T, van Dokkun W Schaafsma G. oligofructose stimulates calcium absorption in adolescents. Am J Clin Nutr 1999; 69: 544-8.
[34] Scholz-Ahrens K, Schaafsma G, van den Heuvel EGMH, Schrezenmeir J. Effects of prebiotics on mineral absorption. Am J Clin Nutr 2001; 73 (Suppl.): 459S-64.
[35] Scholz-Ahrens K, Schrezenmeir J. Inulin, oligofructose and mineral metabolism – experimental data and mechanism. Br J Nutr 87 (Suppl. 2): S179-86.
[36] Ohta A, Ohtsuki M, Baba S, Takizawa T, Adachi T, Kimura S. Effects of fructooligosaccharides on the absorption of iron, calcium and magnesium in iron- deficiency anemic rats. J Nutr Sci Vitaminol 1995; 41: 281-91.
http://dx.doi.org/10.3177/jnsv.41.281
[37] Scholz-Ahrens K, Schrezenmeir J. Effect of oligofructose on dietary calcium on repeated calcium and phosphorus balances, bone mineralization and tubular structure in ovariectomized rats. Br J Nutr 2002; 88: 365-77.
http://dx.doi.org/10.1079/BJN2002661
[38] Coudray C, Bellanger J, Castiglia-Delavaud C, Rémésy C, Vermorel M, Rayssiguier Y. Effects of inulin-type fructans of different chain length and type of branching on intestinal absorption and balance of calcium and magnesium in rats. Eur J Nutr 2003; 42: 91-8.
http://dx.doi.org/10.1007/s00394-003-0390-x
[39] Flickinger EA, Van Loo J, Fahey C. Nutritional responses to the presence of inulin and oligofructose in the diets of domesticated animals: A review. Crit Rev Food Sci Nutr 2003; 43: 19-60.
http://dx.doi.org/10.1080/10408690390826446
[40] Coudray C, Bellanger J, Castiglia-Delavaud C, Rémésy C, Vermorel M, Rayssiguier Y. Effect of soluble or partly soluble dietary fibers supplementation on absorption and balance of magnesium, iron and zinc in healthy young men. Eur J Clin Nutr 1997; 51: 375-80.
http://dx.doi.org/10.1038/sj.ejcn.1600417
[41] Griffin IJ, Davila PM, Abrams, SA. Non-digestible oligosaccharides and calcium absorption in girls with adequate calcium intakes. Br J Nutr 2002; 879 (Suppl. 2): S187-91.
[42] Tahiri M, Tressol JC, Arnaud J, et al. Effect of short-chain fructooligosaccharides on intestinal calcium absorption and calcium status in postmenopausal women: a stable-isotope study. 42 Am J Clin Nutr 2003; 77: 449-57.
[43] Lobo AR, ColliC, Alvares EP, Filisetti TMCC. Effects of fructans-containing yacon (Smallanthus sonchifolius Poepp & Endl.) flour on caecum mucosal morphometry, calcium and magnesium balance, and bone calcium retention in growing rats. Br J Nutr 2007; 97: 776-85.
http://dx.doi.org/10.1017/S0007114507336805
[44] Holloway L, Moynihan S, Abrams SA, Kent K, Hsu AR, Friedlander AL. 2007. Effects of oligofructose-enriched inulin on intestinal absorption of calcium and magnesium and bone turnover markers in postmenopausal women. Br J Nutr 2007; 97: 365-72.
http://dx.doi.org/10.1017/S000711450733674X
[45] Jakeman Sa, Henry CN, Martin BR, et al. Soluble corn fiber increases bone calcium retention in postmenopausal women in a dose-dependent manner: a randomized crossover trial. Am J Cllin Nutr 2016; 104: 837-43.
http://dx.doi.org/10.3945/ajcn.116.132761
[46] Abrams SA, Griffin IJ, Hawthorne KM, et al. A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. Am J Clin Nutr 2005; 82: 471-6.
[47] Jamieson JA, Ryza NA, Taylora CG, Weiler HA. Dietary long-chain inulin reduces abdominal fat but has no effect on bone density in growing female rats. Br J Nutr 2008; 100: 451-9.
http://dx.doi.org/10.1017/S0007114508894378
[48] López-Huertas E, Teucher B, Boza JJ, et al. Absorption of calcium from milks enriched with fructo-oligosaccharides, caseinophosphopeptides, tricalcium phosphate, and milk solids. Am J Clin Nutr 2006; 83: 310-6.
[49] Raschka, L, Daniel H. Mechanisms underlying the effects of inulin-type fructans on calcium absorption in the large intestine of rats. Bone 2005; 37: 728-35.
http://dx.doi.org/10.1016/j.bone.2005.05.015
[50] Raschka, L, Daniel H. Diet composition and age determine the effects of inulin–type fructans on intestinal calcium absorption in rat. European J Nutr 2005; 44: 360-4.
http://dx.doi.org/10.1007/s00394-004-0535-6
[51] Reinhart RA. Magnesium metabolism: A review with special reference to the relationship between intracellular content and serum levels. Arch Intern Med 1988; 148: 2415-20.
http://dx.doi.org/10.1001/archinte.1988.00380110065013
[52] Vormann K. Magnesium: nutrition and metabolism. Mol Asp Med 2013; 24: 27-37.
http://dx.doi.org/10.1016/S0098-2997(02)00089-4
[53] Vaz RTC, Lobo AR, Cocato ML, Coll C. Effects of inulin-type fructans consumption on mineral intestinal absorption and balance in rats fed control andiron-deficient diets. Alim Nutr Araraquara 2010; 21: 7-13.
[54] García-Vieyra MI, Del Real A, López MG. Agave fructans: Their effect on mineral absorption and bone mineral content. J Med Food 2014; 17: 1247-55.
http://dx.doi.org/10.1089/jmf.2013.0137
[55] Legette LCL, Lee WH, Martin BR, Story JA, Campbell JK, Weaver CM. Prebiotics enhance magnesium absorption and inulin-based fibers exert chronic effects on calcium utilization in a postmenopausal rodent model. J Food Sci 2012; 77: 88-94.
http://dx.doi.org/10.1111/j.1750-3841.2011.02612.x
[56] van den Heuvel EGHM, Muijs T, Brouns F, Hendriks HFJ. Short-chain fructo-oligosaccharides improve magnesium absorption in adolescent girls with a low calcium intake. Nutr Res 2009; 29: 229-37.
http://dx.doi.org/10.1016/j.nutres.2009.03.005
[57] Cashman KD, Flynn A. Optimal nutrition: calcium, magnesium and phosphorus. Proc Nutr Soc 1999; 58: 477-87.
http://dx.doi.org/10.1017/S0029665199000622
[58] Calvo MS. Dietary phosphorus, calcium metabolism and bone. J Nutr 1993; 123: 1627-33.
[59] Driessens FMC, Verbeeck RMH, Eds. Biominerals. Boca Raton (FL): CRC Press 1990.
[60] Pérez-Conesa D, López G, Abellán P, Ros G. Bioavailability of calcium, magnesium and phosphorus in rats fed probiotic, prebiotic and synbiotic powder follow-up infant formulas and their effect on physiological and nutritional parameters. J Sci Food Agri 2006; 86: 2327-36.
http://dx.doi.org/10.1002/jsfa.2618
[61] Abbaspour N, Hurrell R, and Kelishadi R. Review on iron and its importance for human health. J Res Med Sci 2014; 19: 164-74.
[62] Lobo AR, Cocato ML, Jorgetti V, de Sác LRM, Nakano EY, Colli C. Changes in bone mass, biomechanical properties, and microarchitecture of calcium- and iron-deficient rats fed diets supplemented with inulin-type fructans. Nutr Res 2009; 29: 873-81.
http://dx.doi.org/10.1016/j.nutres.2009.10.012
[63] Lobo AR, Cocato ML, Borelli P, et al. Iron bioavailability from ferric pyrophosphate in rats fed with fructan-containing yacon (Smallanthus sonchifolius) flour. Food Chem 2011; 126: 885-91.
http://dx.doi.org/10.1016/j.foodchem.2010.11.067
[64] Petry N, Egli I, Chassard C, Lacroix C, Hurrell R. Inulin modifies the bifidobacteria population, fecal lactate concentration, and fecal pH but does not influence iron absorption in women with low iron status. Am J Clin Nutr 2012; 96: 325-31.
http://dx.doi.org/10.3945/ajcn.112.035717
[65] Prasad AS. Discovery and importance of zinc in human nutrition. Fed Proc 1984; 43: 2829-34.
[66] Roohani N, Hurrell R, Kelishadi R, Schulin R. Zinc and its importance for human health: An integrative review. J Res Med Sci 2013; 18: 144-57.
[67] Solomons NW. Biochemical, metabolic, and clinical role of copper in human nutrition. J Am Coll Nutr 1985; 4: 83-105.
http://dx.doi.org/10.1080/07315724.1985.10720069
[68] Williams DM. Copper deficiency in humans. Semin Hematol 1983; 20: 118-28.
[69] Wachnik A. The physiological role of copper and the problems of copper nutritional deficiency. Food-Nahrung 1988; 32: 755-65.
http://dx.doi.org/10.1002/food.19880320811
[70] Coudray C, Feillet-Coudray C, Gueux E, Mazur A, Rayssiguier Y. Dietary inulin intake and age can affect intestinal absorption of zinc and copper in rats. J Nutr 2006; 136: 117-22.
[71] Lopez HW, Coudray C, Levrat-Verny MA, Feillet-Coudray C, Demigné C, Rémésy C. Fructooligosaccharides enhance mineral apparent absorption and counteract the deleterious effects of phytic acid on mineral homeostasis in rats. J Nutr Biochem 2000; 11: 500-8.
http://dx.doi.org/10.1016/S0955-2863(00)00109-1
[72] Younes H, Demigné C, Rémésy C. Acidic fermentation in the caecum increases absorption of calcium and magnesium in the large intestine of the rat. Br J Nutr 1996; 75: 301-14.
http://dx.doi.org/10.1079/BJN19960132
[73] Cashman K. Pebiotics and Ca bioavailability. Curr Issues Intest Microbiol 2003; 4: 21-32.
http://dx.doi.org/10.1007/978-3-642-68275-9_11
[2] Pontis HG, Del Campillo E. Fructan. In: Dey PM, Dixon RA, editors. Biochemistry of storage carbohydrates in green plants. London: Academic Press 1985; p. 205-27.
[3] Pollock CJ, Cairns AJ. Fructan metabolism in grasses and cereals. Annu Rev Plant Physiol Plant Mol Biol 1991; 42: 77-101.
http://dx.doi.org/10.1146/annurev.pp.42.060191.000453
[4] Duggan C, Gannon J, Walker WA. Protective nutrients and functional foods for the gastrointestinal tracts. Am J Clin Nutr 2002; 75: 789-808.
[5] Roberfroid MB. Functional foods: concepts and application to inulin and oligofructose. Br J Nutr 2002; 87 (Suppl. 2): S139-43.
http://dx.doi.org/10.1079/BJN/2002529
[6] Yun JW. Fructooligosaccharides – occurrence, preparation, and application. Enz Microbial Technol 1996; 19: 107-17.
http://dx.doi.org/10.1016/0141-0229(95)00188-3
[7] IUB-IUPAC Joint Commission on Biochemical Nomenclature (JCBN). Abbreviated terminology of oligosaccharide chains. Recommendations 1980. J Biol Chem 1982; 257: 3347-51.
[8] Lewis DH. Nomenclature and diagrammatic representation of oligomeric fructans- a paper for discussion. New Phytol 1993; 124: 583-94.
http://dx.doi.org/10.1111/j.1469-8137.1993.tb03848.x
[9] Waterhouse AL, Chatterton NJ. Glossary of fructan terms. In: Suzuki M, Chatterton NJ, editors. Science and technology of fructans. Boca Raton (FL): CRC Press 1993; p. 1-7.
[10] Shiomi N. Structure of fructo-polysaccharide (asparagosin) from roots of asparagus (Asparagus officinalis L.). New Phytol 1993; 123: 263-70.
http://dx.doi.org/10.1111/j.1469-8137.1993.tb03734.x
[11] Shiomi N, Onodera S, Chatterton NJ, Harrison PA. Separation of fructooligosaccharide isomers by anion-exchange chromatography. Agric Biol Chem 1991; 55: 1427-8.
[12] Shiomi N, Onodera S, Sakai H. Fructo–oligosaccharide content and fructosyltransferase activity during growth of onion bulbs. New Phytol 1997; 136: 105-13.
http://dx.doi.org/10.1111/j.1469-8137.1997.tb04736.x
[13] Stahl B, Linos A, Karas M, Hillenkamp F, Steup M. Analysis of fructans from higher plants by matrix-assisted laser desorption/ionization mass spectrometry. Anal Biochem 1997; 246: 195-204.
http://dx.doi.org/10.1006/abio.1997.2011
[14] WCRF-AICR (World Cancer Research Fund-American Institute of Cancer Research). Food, nutrition and the prevention of cancer: a global perspective. 2007. [Cited 2016 August 5]. Available from: http://www.aicr.org/research/ research_science_expert_report.html
[15] Ness AR, Powles JW. Fruits and vegetables, and cardiovascular disease: A review. Int J Epidemiol 1997; 26: 1-13.
http://dx.doi.org/10.1093/ije/26.1.1
[16] Joshipura KJ, Ascherio A, Mansun J, et al. Fruit and vegetable intake in relation to risk of ischaemic stroke. J Am Med Assoc 1999; 282: 1233-9.
http://dx.doi.org/10.1001/jama.282.13.1233
[17] Johnsen SP, Overvad K, Stripp C, Tjonneland A, Husted SE, Sorensen HT. Intake of fruit and vegetable and the risk of ischaemic stroke in a cohort of Danish men and woman. Am J Clin Nutr 2003; 78: 57-64.
[18] Appel LJ, Moore TJ, Obarzanek E, et al. A clinical trial of the effects of dietary patterns on blood pressure. New Engl J Med 1997; 336: 1117-24.
http://dx.doi.org/10.1056/NEJM199704173361601
[19] Block J, Patterson B, Subar A. fruits, vegetables and cancer prevention: a review of the epidemiological evidence. Nutr Cancer 1992; 18: 1-29.
http://dx.doi.org/10.1080/01635589209514201
[20] Hertog MG, Bueno de Mesquita GB, Fehily A, Sweetnam PM, Elwood PC, Kroumhout D. Fruit and vegetable consumption and cancer mortality in the C aerphilly study. Epidemiol Biomarkers Prev 1996; 5: 673-7.
[21] Olsen M, Gudmand-heyer E. Efficacy, safety, and tolerability of fructooligosaccharides in the treatment of irritable bowel syndrome. Am J Clin Nutr 2000; 72: 1570-5.
[22] Flamm G, Glinsman W, Kritchevsky D, Prosky L, Roberfroid M. Inulin and oligofructose as dietary fiber: A review of the evidence. Crit Rev Food Sci Nutr 2001; 45: 353-62.
http://dx.doi.org/10.1080/20014091091841
[23] Cherbut C. Inulin and oligofructose in the dietary fiber concept. Br J Nutr 2002; 87 (Suppl. 2): S159-62.
http://dx.doi.org/10.1079/BJN2002532
[24] Mitsuoka T, Hidaka H, Eida T. Effects of fructo-oligosaccharides on intestinal microflora. Nahrung 1987; 31: 427-36.
http://dx.doi.org/10.1002/food.19870310528
[25] Spiegel JE, Rose R, Karabell P, Franks VH, Schmitt DF. Safety and benefits of fructooligosaccharides as food ingredients. Food Technol 1994; 1: 85-9.
[26] Tashiro Y, Eida T, Hidaka H. Distribution and quantification of fructooligosaccharides in food materials. Sci Rep Meiji Seiki Kaisha 1992; 31: 35-40.
[27] Tomomatsu H. Health effects of oligosaccharides. Food Technol 1994; 10: 61-5.
[28] Buddington RK, Williams CH, Chen SC, Witherly SA. Dietary supplement of neosugar alters fecal flora and decreases activities of some reductive enzymes in human subjects. Am J Clin Nutr 1996; 63: 709-16.
[29] Farnworth ER. Fructans in human and animal diet. In: Suzuki M, Chatterton NJ, editors. Science and technology of fructans. Boca Raton (FL): CRC Press, 1993; p. 257- 72.
[30] Scheppach W, Luehrs H, Menzel T. Beneficial health effects of low-digestible carbohydrate consumption. Br J Nutr 2001; 85 (Suppl. 1): S23-30.
http://dx.doi.org/10.1079/BJN2000259
[31] Ellegård L, Andersson H, Bosaeus I. Inulin and oligofructose do not influence the absorption of cholesterol, or the excretion of cholesterol, Ca, Mg, Zn, Fe, or bile acids but increases energy excretion in ilestomy subjected. Eur J Clin Nutr 1997; 41: 1-5.
http://dx.doi.org/10.1038/sj.ejcn.1600320
[32] van den Heuvel EGMH, Schaafsma G, Muys T, van Dokkun W. Nondigestible oligosaccharides do not interfere with calcium and nonheme-iron absorption in young, healthy men. Am J Clin Nutr 1998; 67: 445-51.
[33] van den Heuvel EGMH, Muys T, van Dokkun W Schaafsma G. oligofructose stimulates calcium absorption in adolescents. Am J Clin Nutr 1999; 69: 544-8.
[34] Scholz-Ahrens K, Schaafsma G, van den Heuvel EGMH, Schrezenmeir J. Effects of prebiotics on mineral absorption. Am J Clin Nutr 2001; 73 (Suppl.): 459S-64.
[35] Scholz-Ahrens K, Schrezenmeir J. Inulin, oligofructose and mineral metabolism – experimental data and mechanism. Br J Nutr 87 (Suppl. 2): S179-86.
[36] Ohta A, Ohtsuki M, Baba S, Takizawa T, Adachi T, Kimura S. Effects of fructooligosaccharides on the absorption of iron, calcium and magnesium in iron- deficiency anemic rats. J Nutr Sci Vitaminol 1995; 41: 281-91.
http://dx.doi.org/10.3177/jnsv.41.281
[37] Scholz-Ahrens K, Schrezenmeir J. Effect of oligofructose on dietary calcium on repeated calcium and phosphorus balances, bone mineralization and tubular structure in ovariectomized rats. Br J Nutr 2002; 88: 365-77.
http://dx.doi.org/10.1079/BJN2002661
[38] Coudray C, Bellanger J, Castiglia-Delavaud C, Rémésy C, Vermorel M, Rayssiguier Y. Effects of inulin-type fructans of different chain length and type of branching on intestinal absorption and balance of calcium and magnesium in rats. Eur J Nutr 2003; 42: 91-8.
http://dx.doi.org/10.1007/s00394-003-0390-x
[39] Flickinger EA, Van Loo J, Fahey C. Nutritional responses to the presence of inulin and oligofructose in the diets of domesticated animals: A review. Crit Rev Food Sci Nutr 2003; 43: 19-60.
http://dx.doi.org/10.1080/10408690390826446
[40] Coudray C, Bellanger J, Castiglia-Delavaud C, Rémésy C, Vermorel M, Rayssiguier Y. Effect of soluble or partly soluble dietary fibers supplementation on absorption and balance of magnesium, iron and zinc in healthy young men. Eur J Clin Nutr 1997; 51: 375-80.
http://dx.doi.org/10.1038/sj.ejcn.1600417
[41] Griffin IJ, Davila PM, Abrams, SA. Non-digestible oligosaccharides and calcium absorption in girls with adequate calcium intakes. Br J Nutr 2002; 879 (Suppl. 2): S187-91.
[42] Tahiri M, Tressol JC, Arnaud J, et al. Effect of short-chain fructooligosaccharides on intestinal calcium absorption and calcium status in postmenopausal women: a stable-isotope study. 42 Am J Clin Nutr 2003; 77: 449-57.
[43] Lobo AR, ColliC, Alvares EP, Filisetti TMCC. Effects of fructans-containing yacon (Smallanthus sonchifolius Poepp & Endl.) flour on caecum mucosal morphometry, calcium and magnesium balance, and bone calcium retention in growing rats. Br J Nutr 2007; 97: 776-85.
http://dx.doi.org/10.1017/S0007114507336805
[44] Holloway L, Moynihan S, Abrams SA, Kent K, Hsu AR, Friedlander AL. 2007. Effects of oligofructose-enriched inulin on intestinal absorption of calcium and magnesium and bone turnover markers in postmenopausal women. Br J Nutr 2007; 97: 365-72.
http://dx.doi.org/10.1017/S000711450733674X
[45] Jakeman Sa, Henry CN, Martin BR, et al. Soluble corn fiber increases bone calcium retention in postmenopausal women in a dose-dependent manner: a randomized crossover trial. Am J Cllin Nutr 2016; 104: 837-43.
http://dx.doi.org/10.3945/ajcn.116.132761
[46] Abrams SA, Griffin IJ, Hawthorne KM, et al. A combination of prebiotic short- and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. Am J Clin Nutr 2005; 82: 471-6.
[47] Jamieson JA, Ryza NA, Taylora CG, Weiler HA. Dietary long-chain inulin reduces abdominal fat but has no effect on bone density in growing female rats. Br J Nutr 2008; 100: 451-9.
http://dx.doi.org/10.1017/S0007114508894378
[48] López-Huertas E, Teucher B, Boza JJ, et al. Absorption of calcium from milks enriched with fructo-oligosaccharides, caseinophosphopeptides, tricalcium phosphate, and milk solids. Am J Clin Nutr 2006; 83: 310-6.
[49] Raschka, L, Daniel H. Mechanisms underlying the effects of inulin-type fructans on calcium absorption in the large intestine of rats. Bone 2005; 37: 728-35.
http://dx.doi.org/10.1016/j.bone.2005.05.015
[50] Raschka, L, Daniel H. Diet composition and age determine the effects of inulin–type fructans on intestinal calcium absorption in rat. European J Nutr 2005; 44: 360-4.
http://dx.doi.org/10.1007/s00394-004-0535-6
[51] Reinhart RA. Magnesium metabolism: A review with special reference to the relationship between intracellular content and serum levels. Arch Intern Med 1988; 148: 2415-20.
http://dx.doi.org/10.1001/archinte.1988.00380110065013
[52] Vormann K. Magnesium: nutrition and metabolism. Mol Asp Med 2013; 24: 27-37.
http://dx.doi.org/10.1016/S0098-2997(02)00089-4
[53] Vaz RTC, Lobo AR, Cocato ML, Coll C. Effects of inulin-type fructans consumption on mineral intestinal absorption and balance in rats fed control andiron-deficient diets. Alim Nutr Araraquara 2010; 21: 7-13.
[54] García-Vieyra MI, Del Real A, López MG. Agave fructans: Their effect on mineral absorption and bone mineral content. J Med Food 2014; 17: 1247-55.
http://dx.doi.org/10.1089/jmf.2013.0137
[55] Legette LCL, Lee WH, Martin BR, Story JA, Campbell JK, Weaver CM. Prebiotics enhance magnesium absorption and inulin-based fibers exert chronic effects on calcium utilization in a postmenopausal rodent model. J Food Sci 2012; 77: 88-94.
http://dx.doi.org/10.1111/j.1750-3841.2011.02612.x
[56] van den Heuvel EGHM, Muijs T, Brouns F, Hendriks HFJ. Short-chain fructo-oligosaccharides improve magnesium absorption in adolescent girls with a low calcium intake. Nutr Res 2009; 29: 229-37.
http://dx.doi.org/10.1016/j.nutres.2009.03.005
[57] Cashman KD, Flynn A. Optimal nutrition: calcium, magnesium and phosphorus. Proc Nutr Soc 1999; 58: 477-87.
http://dx.doi.org/10.1017/S0029665199000622
[58] Calvo MS. Dietary phosphorus, calcium metabolism and bone. J Nutr 1993; 123: 1627-33.
[59] Driessens FMC, Verbeeck RMH, Eds. Biominerals. Boca Raton (FL): CRC Press 1990.
[60] Pérez-Conesa D, López G, Abellán P, Ros G. Bioavailability of calcium, magnesium and phosphorus in rats fed probiotic, prebiotic and synbiotic powder follow-up infant formulas and their effect on physiological and nutritional parameters. J Sci Food Agri 2006; 86: 2327-36.
http://dx.doi.org/10.1002/jsfa.2618
[61] Abbaspour N, Hurrell R, and Kelishadi R. Review on iron and its importance for human health. J Res Med Sci 2014; 19: 164-74.
[62] Lobo AR, Cocato ML, Jorgetti V, de Sác LRM, Nakano EY, Colli C. Changes in bone mass, biomechanical properties, and microarchitecture of calcium- and iron-deficient rats fed diets supplemented with inulin-type fructans. Nutr Res 2009; 29: 873-81.
http://dx.doi.org/10.1016/j.nutres.2009.10.012
[63] Lobo AR, Cocato ML, Borelli P, et al. Iron bioavailability from ferric pyrophosphate in rats fed with fructan-containing yacon (Smallanthus sonchifolius) flour. Food Chem 2011; 126: 885-91.
http://dx.doi.org/10.1016/j.foodchem.2010.11.067
[64] Petry N, Egli I, Chassard C, Lacroix C, Hurrell R. Inulin modifies the bifidobacteria population, fecal lactate concentration, and fecal pH but does not influence iron absorption in women with low iron status. Am J Clin Nutr 2012; 96: 325-31.
http://dx.doi.org/10.3945/ajcn.112.035717
[65] Prasad AS. Discovery and importance of zinc in human nutrition. Fed Proc 1984; 43: 2829-34.
[66] Roohani N, Hurrell R, Kelishadi R, Schulin R. Zinc and its importance for human health: An integrative review. J Res Med Sci 2013; 18: 144-57.
[67] Solomons NW. Biochemical, metabolic, and clinical role of copper in human nutrition. J Am Coll Nutr 1985; 4: 83-105.
http://dx.doi.org/10.1080/07315724.1985.10720069
[68] Williams DM. Copper deficiency in humans. Semin Hematol 1983; 20: 118-28.
[69] Wachnik A. The physiological role of copper and the problems of copper nutritional deficiency. Food-Nahrung 1988; 32: 755-65.
http://dx.doi.org/10.1002/food.19880320811
[70] Coudray C, Feillet-Coudray C, Gueux E, Mazur A, Rayssiguier Y. Dietary inulin intake and age can affect intestinal absorption of zinc and copper in rats. J Nutr 2006; 136: 117-22.
[71] Lopez HW, Coudray C, Levrat-Verny MA, Feillet-Coudray C, Demigné C, Rémésy C. Fructooligosaccharides enhance mineral apparent absorption and counteract the deleterious effects of phytic acid on mineral homeostasis in rats. J Nutr Biochem 2000; 11: 500-8.
http://dx.doi.org/10.1016/S0955-2863(00)00109-1
[72] Younes H, Demigné C, Rémésy C. Acidic fermentation in the caecum increases absorption of calcium and magnesium in the large intestine of the rat. Br J Nutr 1996; 75: 301-14.
http://dx.doi.org/10.1079/BJN19960132
[73] Cashman K. Pebiotics and Ca bioavailability. Curr Issues Intest Microbiol 2003; 4: 21-32.
Downloads
Published
2016-10-07
How to Cite
Benkeblia, N. (2016). Fructans and Mineral Nutrition. Journal of Nutritional Therapeutics, 5(3), 68–74. https://doi.org/10.6000/1929-5634.2016.05.03.2
Issue
Section
Articles
License
Policy for Journals/Articles with Open Access
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are permitted and encouraged to post links to their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work
Policy for Journals / Manuscript with Paid Access
Authors who publish with this journal agree to the following terms:
- Publisher retain copyright .
- Authors are permitted and encouraged to post links to their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work .
