A Novel Method for Viral Conjunctivitis Detection using CNN-Based Image Analysis

Authors

  • Jalindar Gandal School of Computer Science and Engineering, Dr. Vishwanath Karad MIT World Peace University, Kothrud, Pune – 411038, Maharashtra, India
  • Walid Ayadi Mechatronics and Intelligent Systems, Abu Dhabi Polytechnic, UAE
  • Yasser Farhat Academic Support Department, Abu Dhabi Polytechnic, Abu Dhabi, UAE
  • P.S. Metkewar School of Computer Science and Engineering, Dr. Vishwanath Karad MIT World Peace University, Kothrud, Pune – 411038, Maharashtra, India
  • Showkat A. Bhat Symbiosis School of Economics, Symbiosis International (Deemed University), Pune, India
  • Aafaq A. Rather Symbiosis Statistical Institute, Symbiosis International (Deemed University), Pune, India

DOI:

https://doi.org/10.6000/1929-6029.2025.14.57

Keywords:

Viral Conjunctivitis, outbreak, Eye flu, Image processing, CNN, Medical imaging, Ophthalmology

Abstract

Viral conjunctivitis, also known as “Eye Flu,” presents significant public health challenges worldwide. India has recently witnessed a surge in cases, affecting numerous people and causing widespread concerns. This research delves into the realm of medical image processing and deep learning to address the pressing need for accurate and efficient detection of viral conjunctivitis, a highly contagious ocular infection. Leveraging advancements in computer vision and convolutional neural networks (CNNs), the study focuses on the development and evaluation of a robust diagnostic system capable of discerning viral conjunctivitis from other common forms of conjunctivitis, namely allergic and bacterial.

Challenges in using image processing for disease detection include the need for large amounts of descriptive data to train machine learning models, ensuring the accuracy and reliability of image analysis algorithms, and addressing data privacy and security concerns. Future directions in this field may include developing more advanced deep learning models that can handle complex medical imaging data, integration of imaging technology and other diagnostic tools to diagnose diseases and learn how to use it in real-time for fast processing. and more efficient diagnosis. Additionally, efforts should be made to standardize image processing protocols in different healthcare settings to facilitate sharing and comparison of medical imaging data for research and clinical purposes. Overall, more research and collaboration between medical, informatics, and image processing experts is essential in developing future image processing applications for disease detection.

The methodology encompasses the acquisition of a diverse dataset comprising annotated images of ocular conditions, rigorous preprocessing techniques to standardize image quality, and the implementation of three distinct CNN architectures: ResNet, VGG, and GoogleNet. These architectures were selected for their proven efficacy in medical image analysis and classification tasks. Through extensive experimentation and rigorous validation, the research elucidates the efficacy of each architecture in accurately classifying conjunctival diseases, with a particular emphasis on delivering actionable diagnostic outcomes.

References

Sié A, Diarra A, Millogo O, Zongo A, Lebas E, Bärnighausen T, Oldenburg CE. Seasonal and temporal trends in childhood conjunctivitis in Burkina Faso. The American Journal of Tropical Medicine and Hygiene 2018; 99(1): 229. DOI: https://doi.org/10.4269/ajtmh.17-0642

Farswan A, Singh MF, Dhasmana A, Bahuguna V, Kumar G, Jadon VS. Enhancing Diagnosis and Management of Conjunctivitis: Innovations, and Evidence-Based Strategies. In 2024 International Conference on Healthcare Innovations, Software and Engineering Technologies (HISET) IEEE 2024; pp. 160-164.

Stalin JSD. Tamil Nadu sees ‘Madras Eye’Surge, 1.5 lakh conjunctivitis cases in monsoon so far. NDTV 2022.

Arslan OE. Anatomy and physiology of retina and posterior segment of the eye. In Drug Delivery for the Retina and Posterior Segment Disease. Cham: Springer International Publishing 2018; pp. 3-33. DOI: https://doi.org/10.1007/978-3-319-95807-1_1

Azari AA, Arabi A. Conjunctivitis: a systematic review. Journal of Ophthalmic & Vision Research 2020; 15(3): 372.

Naderi K, Gormley J, O’Brart D. Cataract surgery and dry eye disease: A review. European Journal of Ophthalmology 2020; 30(5): 840-855. DOI: https://doi.org/10.1177/1120672120929958

Musa M, Bale BI, Suleman A, Aluyi-Osa G, Chukwuyem E, D’Esposito F, Zeppieri M. Possible viral agents to consider in the differential diagnosis of blepharoconjunctivitis. World Journal of Virology 2024; 13(4): 97867. DOI: https://doi.org/10.5501/wjv.v13.i4.97867

Mustafa HE, Ibrahim IA, Elfaki BA. Complementary Alternative Medicine for Viral Conjunctivitis treatment. Cuestiones de Fisioterapia 2025; 54(5): 240-252.

Azari AA, Barney NP. Conjunctivitis: a systematic review of diagnosis and treatment. JAMA 2013; 310(16): 1721-1730. DOI: https://doi.org/10.1001/jama.2013.280318

Saxena R, Sharma P, Gopal S. Pediatric Ophthalmology Expert Group. National consensus statement regarding pediatric eye examination, refraction, and amblyopia management. Indian Journal of Ophthalmology 2020; 68(2): 325-332. DOI: https://doi.org/10.4103/ijo.IJO_471_19

Singha A, Thakur RS, Patel T. Deep learning applications in medical image analysis. Biomedical Data Mining for Information Retrieval: Methodologies, Techniques and Applications 2021; 293-350. DOI: https://doi.org/10.1002/9781119711278.ch11

Le Goallec A, Diai S, Collin S, Vincent T, Patel CJ. Deep learning of fundus and optical coherence tomography images enables identification of diverse genetic and environmental factors associated with eye aging. medRxiv 2021; 2021-06. DOI: https://doi.org/10.1101/2021.06.24.21259471

Shojaeinia M, Moghaddasi H. Advances in Deep Learning for Eye Disease Diagnosis: Applications, Challenges, and Future Directions. Journal of Innovations in Computer Science and Engineering (JICSE) 2025; 2: 33-41.

He K, Zhang X, Ren S, Sun J. Deep residual learning for image recognition. In Proceedings of the IEEE conference on computer vision and pattern recognition 2016; pp. 770-778. DOI: https://doi.org/10.1109/CVPR.2016.90

Simonyan K, Zisserman A. Very deep convolutional networks for large-scale image recognition. arXiv preprint arXiv 2014; 1409.1556.

Szegedy C, Liu W, Jia Y, Sermanet P, Reed S, Anguelov D, Rabinovich A. Going deeper with convolutions. In Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition 2015; pp. 1-9. DOI: https://doi.org/10.1109/CVPR.2015.7298594

Jia H, Zhang J, Ma K, Qiao X, Ren L, Shi X. Application of convolutional neural networks in medical images: a bibliometric analysis. Quantitative Imaging in Medicine and Surgery 2024; 14(5): 3501. DOI: https://doi.org/10.21037/qims-23-1600

World Health Organization. Eye care in health systems: guide for action. World Health Organization 2022.

Chatterjee S, Gangwe AB, Agrawal D. Health-seeking behaviors during an outbreak of acute conjunctivitis in Central India. Indian Journal of Ophthalmology 2025; 73(1): 45-51. DOI: https://doi.org/10.4103/IJO.IJO_849_24

Paliwal R, Paliwal SR. Nanomedicine, Nanotheranostics and Nanobiotechnology: Fundamentals and Applications. CRC Press 2025. DOI: https://doi.org/10.1201/9781003130055

Azari AA, Arabi A. Conjunctivitis: a systematic review. Journal of Ophthalmic & Vision Research 2020; 15(3): 372. DOI: https://doi.org/10.18502/jovr.v15i3.7456

Balazadeh V, Cooper M, Pellow D, Assadi A, Bell J, Coatsworth M, Krishnan RG. Red teaming large language models for healthcare. arXiv preprint arXiv 2025; 2505.00467.

Bhat N, Patel R, Reddy JJ, Singh S, Sharma A, Multani S. Knowledge and awareness of eye flu among the dentists and dental auxiliaries of Udaipur City, Rajasthan. International Journal of Preventive Medicine 2014; 5(7): 920.

Mohanasundaram AS, Gurnani B, Kaur K, Manikkam R. Madras eye outbreak in India: Why should we foster a better understanding of acute conjunctivitis? Indian Journal of Ophthalmology 2023; 71(5): 2298-2299. DOI: https://doi.org/10.4103/IJO.IJO_3317_22

Shivaji S. Antimicrobial Resistance of the Diseased Human Eye: Conjunctivitis. In Antimicrobial Resistance of the Human Eye. CRC Press 2024; pp. 372-417. DOI: https://doi.org/10.1201/9781003451105-13

Shivaji S. Antimicrobial Resistance of the Human Eye. CRC Press 2024. DOI: https://doi.org/10.1201/9781003451105

Iqbal J, Serhan HA, Al-Qahtani OM, Alharami A, Alhebail MS. Infectious Agents in Ophthalmology: Clinical Perspectives. Mahi Publication 2024.

Farswan A, Singh MF, Dhasmana A, Bahuguna V, Kumar G, Jadon VS. Enhancing Diagnosis and Management of Conjunctivitis: Innovations, and Evidence-Based Strategies. In 2024 International Conference on Healthcare Innovations, Software and Engineering Technologies (HISET). IEEE 2024; pp. 160-164. DOI: https://doi.org/10.1109/HISET61796.2024.00056

Patel DS, Arunakirinathan M Stuart A, Angunawela R. Allergic eye disease. BMJ 2017; 359. DOI: https://doi.org/10.1136/bmj.j4706

Leung AK, Hon KL, Wong AH, Wong AS. Bacterial conjunctivitis in childhood: etiology, clinical manifestations, diagnosis, and management. Recent Patents on Inflammation & Allergy Drug Discovery 2018; 12(2): 120-127. DOI: https://doi.org/10.2174/1872213X12666180129165718

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Published

2025-10-01

How to Cite

Gandal, J. ., Ayadi, W. ., Farhat, Y. ., Metkewar, P. ., Bhat, S. A. ., & Rather, A. A. . (2025). A Novel Method for Viral Conjunctivitis Detection using CNN-Based Image Analysis. International Journal of Statistics in Medical Research, 14, 601–615. https://doi.org/10.6000/1929-6029.2025.14.57

Issue

Section

Special Issue: Trends in Artificial Intelligence and Machine Learning in Healthcare

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