jbas

journal-basic-applied-scien

Depression: An Insight and Need for Personalized Psychological Stress Monitoring and Management
Pages 177-182
Sandeep Kumar Vashist and E. Marion Schneider

DOI: http://dx.doi.org/10.6000/1927-5129.2014.10.25

Published: 23 May 2014

Open Access

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journal-basic-applied-scien

Reduction of Pain and Depression in Occlusal Splint-Based Treatment for TMD is Accompanied with Increase in Urinary Serotonin
Pages 183-188
M.B. Nunes, J. Oliveira and R. Brito

DOI: http://dx.doi.org/10.6000/1927-5129.2014.10.26

Published: 23 May 2014

Open Access

Abstract: The aim of this study was to assess the parallel effects of an occlusal splint-based intervention for TMD on urinary serotonin levels, depression and pain. Previous RCT studies have shown that occlusal splint-based treatment reduce pain and depression, but have not measured serotonin. 15 patients (four males and 11 females) completed an intervention protocol with a silicone dental splint for 60 days. Patients were assessed before and after treatment for urinary serotonin levels, TMD-related pain and depression symptoms (self-reports). Results showed a significant increase in urinary serotonin levels between the two assessments along with a reduction in pain and depression. Overall results suggest that the positive effects of occlusal-based treatment on physical and mental health could be related to increases in serotonin levels.

Keywords: TMD, Occlusal splint, Urinary Serotonin, Depression, Pain.
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Identifying Coping Profiles and Profile Differences in Role Engagement and Subjective Well-Being
Pages 189-204
Saija Mauno, Marika Rantanen and Asko Tolvanen

DOI: http://dx.doi.org/10.6000/1927-5129.2014.10.27

Published: 23 May 2014

Open Access

Abstract: Coping strategies are not necessarily mutually exclusive and can be used simultaneously, a fact which has rarely been examined in coping research. We examined what kinds of coping profiles could be found in data concerning Finnish health care and service employees (n = 2756). We also studied whether role engagement (family-to-work-enrichment, work-to-family-enrichment, emotional energy at work, and work engagement) and subjective well-being (life, parental, and marital satisfaction, and psychological distress) differ between coping profiles. The data were analyzed through latent profile (LPA) and covariance analyses (Ancovas). LPA revealed seven distinct coping profiles: two active groups, one passive group, one low and two high copers’ groups and one moderate group. These results indicate that coping strategies are not mutually exclusive and that people might use different strategies simultaneously. The covariance analyses revealed that the most significant differences concerned role engagement: active copers showed higher role engagement (e.g. enrichment, work engagement) than moderate or low copers. The findings imply that the indicators of role engagement deserve more attention in coping research in healthy working adults.

Keywords: Coping profiles, coping strategies, latent profile analysis, person-oriented approach, role engagement, well-being.
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The Proliferation and Migration-Enhancing Effects of Vitronectin in SMMC 7721 Cells: A Pilot Study
Pages 205-211
Wei Zhu, Konghe Hu, WenXue Li, Guangyu Yang, Jianling Chen, Chuanxi Fu and Qiansheng Hu

DOI: http://dx.doi.org/10.6000/1927-5129.2014.10.28

Published: 23 May 2014

Open Access

Abstract: To understand the effects of Vitronectin on cell proliferation and migration in the cell line of hepatocellular carcinoma, SMMC 7721, the effects of Vitronectin on cell proliferation rate or on the prevention of the cells from the apoptotic stimuli were appraised with WST-1 assay; and the morphology of b-Tubulin was observed with con-focal microscope. The effect on migration was detected with transwell chamber. The results show that Vitronectin helps the cells adhere to Petri dish as well as the sustaining of the morphology of b-Tubulin. Vitronectin could enhance the proliferation rate of SMMC 7721 with the concentration-effect mode, and could protect the cells from the stimuli of apoptosis inducer. As to cell migration, the results show that Vitronectin enhance cell migration across the membrane of transwell chamber. According the results, the conclusion could be made that Vitronectin might play important roles in the following biological effects, such as sustaining the morphology of the tumor cells, enhancing the proliferation as well as the migration.

Keywords: Vitronectin, Hepatocellular Carcinoma, Proliferation, Tumor Cell Migration.
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